Effect of a 10-week combined exercise training on new fatty liver markers in women with type 2 diabetes

Introduction: Fatty liver is a condition in people with type 2 diabetes mellitus (T2DM). The purpose of this study is to examine the effects of combined training on novel hepatic steatosis indices (fatty liver index (FLI), accumulation product (LAP), hepatic steatosis index (HSI), and Framingham steatosis index (FSI)) in women with type 2 diabetes. Methods: 35 female with type 2 diabetes were assigned to combined training (n = 17) and control (n = 18). Intervention consisted of combined (aerobic-strength training) for 10 weeks. Data were analyzed using dependent t test to compare pretest and posttest in each group. The Analysis of covariance (ANCOVA) was used to compare the amount of changes in experimental and control training groups after 10 weeks.  Results: The results of the analysis of covariance showed that 10 weeks of combined training caused a non-significant decrease in HSI (P = 0.596), FSI (P = 0.312), FLI (P = 0.327) and a significant decrease in LAP (P = 0.334) compared to the control group.  Conclusion: The results show that 10-week combined training results in a significant decrease in LAP index and a non-significant reduction in FSI, HSI, and FLI indices of women with type 2 diabetes. Therefore, combined training recommended for improve the fatty liver in women with type 2 diabetes.